Part of the High-Risk, High-Reward Research program, the award supports early career investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the NIH mission.

• Single PI only
• Must have Early Stage Investigator status (completed doctoral degree or postgraduate clinical training within last 10 years and never received a substantial NIH independent research award)
• No preliminary data required
• Minimum of 25% research effort
• $1.5 million in direct costs split into two multi-year segments

See the Award Overview for more information.